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KMID : 0939920140460030312
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대한암학회지
2014 Volume.46 No. 3 p.312 ~ p.316
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Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission
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Lee Won-Sup
Hwang Ji-Hyen
Kim Moon-Jin
Go Se-Il
Lee An-Na
Song Haa-Na
Lee Min-Jeong
Kang Myung-Hee
Kim Hoon-Gu
Lee Jeong-Hee
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Abstract
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Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. It is well-established that patients who are diagnosed with SPTL usually respond poorly to chemotherapy, showing fatal outcome. As a first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the treatment of SPTL, the efficacy of cyclosporine A has been recently reported in relapsed SPTL after anthracycline-based chemotherapy. However, it is still not clear whether cyclosporine A can be used as a first-line treatment against SPTL. Here, we report a case of SPTL, which achieved complete remission for nine years after first-line cyclosporine A therapy. This study suggests that cyclosporine A can induce a complete long-term remission as a first-line treatment.
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KEYWORD
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Subcutaneous panniculitis-like T cell lymphoma, Cyclosporine A, Remission
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